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In the mid-1990s, renowned Israeli researcher Dr. Ralph Mechaoulam, professor of Medicinal Chemistry at Hebrew University in Jerusalem, made an exciting discovery that would forever change how we look at our biological relationship to plant medicine. Dr. Mechaoulam discovered a subtle system within the body that seemed to have a balancing effect on every other system. He called it the Endocannabinoid (EC) System and it can be found in all mammals, including humans.
The EC system consists of a series of molecular receptors that are designed to receive cannabinoids. In particular this includes cannabidiol (CBD) and tetrahydrocannabinol (THC) as well as other related substances such as cannabigerol (CBG) and cannabinol (CBN).
Prior research in the 1980s led Mechaoulam and others to pinpoint two main receptors for cannabinoids − cannabinoid 1 (CB1) and cannabinoid 2 (CB2). Researchers at the time also defined the natural substances called endocannabinoids, which our body produces on its own in a similar way it produces endorphins. Phytocannabinoids (namely THC, CBD, and their variants), on the other hand, come directly from the cannabis plant.
Cannabinoid receptors CB1 and CB2 are designed by the body to be specific targets for THC, while our natural endocannabinoids help to synthesize it. The process of THC-cannabinoid receptor binding and what this does for the body is what researchers have been studying for over two decades. They are doing this in order to find out exactly how cannabis works in healing cancer.
Microbiologist Dr. Christine Sanchez of Compultense Univeristy in Madrid, Spain has been studying cannabinoids and cancer since the early 2000s. She was the first to discover the antitumor effects of cannabinoids.
“We now know that the endocannabinoid system regulates a lot of biological functions such as appetite, food intake, motor function, reproduction and many others and that is why the plant has such a wide therapeutic potential,” says Dr. Sanchez in a video interview for the web-based cable channel Cannabis Planet.
REPRODUCED FROM: https://thetruthaboutcancer.com/cannabis-and-cancer/